Main Article Content
Abstract
From 1st of march 2005 to 29th of February 2006. 1000 children under 5 years age with acute gastroenteritis seen in outpatient and inpatient departments of child and maternity teaching hospital in the city of Nassiryia were studied .
One Hunderd children under 5 years of age admitted to the hospital for reasons other than vomiting and diarrhea, were randomly selected and regarded as control.
Stool specimens of both study and control patients were examined for the presence of Hunman Rota Virus antigen by latex agglutination test(LA) .
Human Rota Virus antigen was detected in stool samples of 39% of the study cases and 2% of the control group.
The antigen was detected more in specimens of infants particularly those between 6-18 months of age.
The incidence of infection was lowest among exclusive breast –fed infants.
Males were more commonly affected than females , but no difference was seen among different socio-economic classes.
Human Rota Virus antigen was detected throughout the period of the study with significant increase during winter months.
Children with acute Rota Virus gastroenteritis have certain clinical features and laboratory result, these features and results collectively can be of help in presumption of a clinical diagnosis for the condition .
Article Details
References
- - Al-Naqshabandi T .Y. (1993) . Rota Virus gastroenteritis among infants and young children in Nassriya : 58.
- - Bartlett A. V., Moore M., Gary G . W., Starko K.M., Erben J.J., Meredith A.B (1985). Diarrhoeal illness among infants and toddlers in day care centers . Epidemiology and pathogens.J. Pediatr .107:495.
- - Bishop R.F., Davidosn G.P., and Holmes I.H. (1975) . Virus particles in epithelial cells of duodenal mucosa from children with acute non-bacterial gastroenteritis . Lancet, 2:1281.
- - Black R. E., Merson, M.H., Brcker S., Abdul Alim A.R.M., and Haq, I., (1982). Longitudinal studies of infections diseases and physical growth of children in rural Bangladesh Am.J. (1981)
- - Black ,R.E., Merson,M.H., Rahman , A.S.M.M , Yunis ., Alim , A.R.M.A., Hug .I., Yolken , R. H., Curling G. T., (1980) . A two-year study of bacterial viral and parasitic Agents associated with diarrhea in rural Bangladesh . J. infect Dis . 142:660.
- - Bradhan P.K. , Salam M.A. , A.M. Gastric emptying of liquid in children suffering from acute rotaviral gastro-enteritis . Gut. 1992. 33:26.
- - Bryden, A.S., Davies, H.A., Thouless, M.E., and Flewett, T.H.Moris, C.A., and Oliver, P.(1975) . Rotavirus enteritis in the West Medlands during 1974. Lancet, 2:241.
- - Carlson , J.A.K. , Middleton , P.J., Szymanski , M.T.,Huber, J., Petric, M.(1978). Fatal rotavirus gastroenteritis .Am. J. Dis. Chil . 132:477 .
- - Cone , R., Mohan, K., Thouless, M., Corey, L. (1988). Nosocomial transmission of rotavirus infection . Pediatric . Infect. Dis. J., 7:103 .
- - Dennehy , P.H. Peter , G. (1985). Risk factors associated with nosocomial rotavirus infection .Am. J. Dis. Child. 139:935 .
- - De Zoyza, I., and Feacham , R.G.,(1985). Intervention for the control of diarrhoeal diseases among young children ; Rotavirus & cholera immunization .Bull.W.H.O. 63:569 .
- - Dowling , J.M., and Wynne . H. (1981). Role of enteric adenovirus and rotavirus in infantile gastroenteritis . Lancet, 2:305.
- - Dutta, S., Khalfan , S.A., Baig, B.H., philipose , L., and Fulavfil , R.(1990) . Epidemiology of Rotavirus dirrhoea in children under five years in Bahrain . Intern .19:722 .
- - Ellis, M.E., Watson, B., Mandal, B.K., Dunbar,E.M., Craske, J., Curry, A., Roberts J., and Lomax. J., (1984). Microorganisms in gastroenteritis . Arch. Dis. Child. 59:848.
- - Feachmen , R.G., and Koblinsky M.A., Intervention for control of Giassudin ,
- diarrhoeal diseases among children : Promotion of breast Feeding , Bulletin of the W.H.O. 62.1984 p271-291 .
- - Giassudin, A.S., M., Boryswick, G., and Absedra, A. (1989) Rotavirus associated diarrhoeal disease in Libyan infants up to one year of age . The 8th Medical Conference of the Kuwait Medical Association 1989.
- - Goldwater , P.N., Chrystie I.L., Banatval. J.E. (1979). Rotavirus and the respiratory tract. B.Med. J. 2:1551 .
- - Guarino, A., Guandalini, S., Al-bano, F., Mascia, A.,G.,Rubino. A. (1991). Enteral immunoglobulins for treatment of protracted rotaviral diarrhoea pediatric . Infect. Dis J. 10:612 .
- - Gurwith , M., Wenman, W.,Hinde , D., Felthman , S., and Greenberg, H. (1981) . A prospective study of rotavirus infection in infants and young children . J. infect. Dis. 144:218 .
- - Hart C.A. and Ibrahim O.S. (1989). Rotavirus and gastroenteritis . Postgraduate Doctor 1989 12:252 .
- - Hanson , L.A., Hofvander , Y., Lindquist , B., Zetterstrom. R. (1985). Breast feeding as a protection against gastro-enteritis and other infections . Acta.Pediat. Scand.74:641.
- - Hassony , H.J., and Abdul-Aziz S.M. (1989). Rotavirus among childhood diarrhoea in Basrah . Med. J. Basrah University .
- - Ho, M.S., Glass, R.I. , Pinsky , P.F , Anderson , L.J. (1989). Rotavirus as a cause of diarrhoea morbidity and mortality in the United States . J. Infect. Dis. 158:1112.
- - Hyams, J.S., Krause , P.J. , and Gleason , P.A.,(1981). Lactose malabsorption following rotavirus infection in young children . J. Pediatr. 98:316 .
- - Kapikian , A.Z., Kim, H.W., Wyatt, R.G., Cline , W.L., Arrobio, J.O., Brandt, C.D. , Rodriguez, W.J., Sack , D.A. , Chanock , R.M. , and Parrott , R.H., and chanok , R.M. (1980). Approaches to immunization of infants and young children against gastroenteritis due to rotavirus , Rev. Infect. Dis. 2:159.
- - Keidon I. , Shift I. , Kerem G. Passwell J.H., (1992) Pediat. Infect. Dis. Jour. 11:773 .
- - Kim K.H Yang-J-M. Joo-S-I. Cho-Y-G. Glass-RI. Cho-Y-G. Importance of rotavirus and adenovirus type 40 and 41 in acute gastroenteritis in Korean children J. Clini-Microbiol . 1990 . 28:2279 .
- - Lewis, H.M. , Parry J.U., Davies , H.A., Parry, R.D. , Mott A. , Dourmashkin , R. R., Sanderson , P.J, Tyrell , D.A.J, and valman. H.B. (1979). A year-experence of the ritavirus syndrome and it's association with respiratory illness . Arch. Dis Child. ; 54:339 .
- - Mitchell, J. , and Skelton , M. M. (1988) . Diarrhoeal infections. 37:195.
- - Nabeel I. A. , Al-Hadithi . T., Al-Atar. A. 1986 . Rotavirus and acute infectious gastro-enteritis in children uder five years of age: 77 .
- - Maki, M. (1981) . A prospective clinical study of rotavirus diarrhoea in young children. Acta. Pediatr. Scand 71:107 .
- - Persson , B.L. , Thoren A. , Tufvesson, B. and Walder , M. (1982) . Diarrhoea Swedish infants . Acta. Pediatr . Scand 71:909 .
- - Robert M.K., Stanly A.P. Rotavirus . Nelson Text Book of Pediatric . 14th ed. USA: W.P . Saunders Company 1992:831.
- - Ruuska, T., and Vesikari , T. (1990). Rotavirus disease in finish children: use of numerical scores for clinical serverity of diarrhoea episodes. Scand. J. Infect. Dis. 22:259.
- - Saulsbury , F.T., Winkelstein , J.A., and Yolken , R.H., (1980). Chronic Rotavirus infection in immune deficiency . J. Pediatr. 97:61.
- - Sengupta , P.G., Sen, D., Saha, M.R., Niyogi , S., Deb, B.C., Pal, S.C., (1981) . An epidemic of Rotavirus diarrhoea in Manipure India Transactions of the Royal Society of tropical Medicine and hygiene. 75:521.
- - Shephered R.W., Traslow, S., Walker-Smith, J.A, Bird, R., cutting, W., Darnell , R., and barker, C. M. (1975). Infantile gastroenteritis : A clinical study of reovirus-like agent infection. Lancet, 2:1082 .
- - Stoll, B.J., Glass, R.I., Bane, H., Huq, M., Khan, M.U.,Ahned, H. (1983) . Vlue of stool examination in patients with diarrhoea Br. Med. J. 28:2037.
- - Soenarto , Y. , Sebodo, T. Suryantoro , P. , Krisnomurti , Haksohusodo , S. Uyas , Kusniyo , Ristanto , Romas , M. A., Noerhajati , Muswiroh , S., Rohde, J.E., Ryan , N.J., Luke, R.K.J., Barnes, G.L., and Bishop, R.F., (1983). Bacteria , parasitic agents and Rotavirus associated with acute diarrhoea in hospital inpatient Indonesian children. Royal Socity of Tropical Medicine and hygiene . 77:724.
- - Tallet , S., Mackenzie, C. , Middleton , P., Kerzner, B., and Hamilton, R., (1977) Clinical, laboratory and epidemiological features of viral gastroenteritis in infants and children . Pediatr. 60:217.
- - Thouless, M.E., Bryden, A.S. , Flewett , T.H., (1977) . Rotavirus neutralization by human milk Br. Med. J. 4:1390.
- - Uhnoo, I., E., olding stenkvist, and A., Kveugev (1986). Clinical features of acute gastroenteritis associated with rotavirus , enteric adenoviruses , and bacteria Arch. Dis. Child. 61:732 .
- - Walker-Smith. J., (1978. Rotavirus gastroenteritis .Arch. Dis child 53:355 .
- - Waller , D.K., Samad Talukolar , M.A. , Carvalho, A.N., and Al-Amawy , A.M., O.(1984) . Rotavirus diarrhoea among pediatric inpatients at armed forced hospital , Riyadh . Saudi. Medical Journal 5:49.
- - Weinbery, R.J., Tipton , G.Klish, W.J., and Brown , M.R., (1984). Effect of breast feeding on morbidity of Rotavirus gastroenteritis , Pediatric , 74:250.
- - Williams, E.K., Lohr., J.A., and Guerrant, R.L.,(1986). Acute infectious diarrhoea , diagnosis treatment and prevention . Pediatr. Infect. Dis. 3:244.
- - Yolken, R.H., Wyatt, R.G. , Mata, L. , Urrutia, J.J., Garcia , B., Chabock , , R.M. , and Kapikian , A.Z. (1978). Secretary Antibody directed against rotavirus in human milk measurement by means of enzyme-linked immunosorbent assay J. Pediatr. 93:916.
References
- Al-Naqshabandi T .Y. (1993) . Rota Virus gastroenteritis among infants and young children in Nassriya : 58.
- Bartlett A. V., Moore M., Gary G . W., Starko K.M., Erben J.J., Meredith A.B (1985). Diarrhoeal illness among infants and toddlers in day care centers . Epidemiology and pathogens.J. Pediatr .107:495.
- Bishop R.F., Davidosn G.P., and Holmes I.H. (1975) . Virus particles in epithelial cells of duodenal mucosa from children with acute non-bacterial gastroenteritis . Lancet, 2:1281.
- Black R. E., Merson, M.H., Brcker S., Abdul Alim A.R.M., and Haq, I., (1982). Longitudinal studies of infections diseases and physical growth of children in rural Bangladesh Am.J. (1981)
- Black ,R.E., Merson,M.H., Rahman , A.S.M.M , Yunis ., Alim , A.R.M.A., Hug .I., Yolken , R. H., Curling G. T., (1980) . A two-year study of bacterial viral and parasitic Agents associated with diarrhea in rural Bangladesh . J. infect Dis . 142:660.
- Bradhan P.K. , Salam M.A. , A.M. Gastric emptying of liquid in children suffering from acute rotaviral gastro-enteritis . Gut. 1992. 33:26.
- Bryden, A.S., Davies, H.A., Thouless, M.E., and Flewett, T.H.Moris, C.A., and Oliver, P.(1975) . Rotavirus enteritis in the West Medlands during 1974. Lancet, 2:241.
- Carlson , J.A.K. , Middleton , P.J., Szymanski , M.T.,Huber, J., Petric, M.(1978). Fatal rotavirus gastroenteritis .Am. J. Dis. Chil . 132:477 .
- Cone , R., Mohan, K., Thouless, M., Corey, L. (1988). Nosocomial transmission of rotavirus infection . Pediatric . Infect. Dis. J., 7:103 .
- Dennehy , P.H. Peter , G. (1985). Risk factors associated with nosocomial rotavirus infection .Am. J. Dis. Child. 139:935 .
- De Zoyza, I., and Feacham , R.G.,(1985). Intervention for the control of diarrhoeal diseases among young children ; Rotavirus & cholera immunization .Bull.W.H.O. 63:569 .
- Dowling , J.M., and Wynne . H. (1981). Role of enteric adenovirus and rotavirus in infantile gastroenteritis . Lancet, 2:305.
- Dutta, S., Khalfan , S.A., Baig, B.H., philipose , L., and Fulavfil , R.(1990) . Epidemiology of Rotavirus dirrhoea in children under five years in Bahrain . Intern .19:722 .
- Ellis, M.E., Watson, B., Mandal, B.K., Dunbar,E.M., Craske, J., Curry, A., Roberts J., and Lomax. J., (1984). Microorganisms in gastroenteritis . Arch. Dis. Child. 59:848.
- Feachmen , R.G., and Koblinsky M.A., Intervention for control of Giassudin ,
diarrhoeal diseases among children : Promotion of breast Feeding , Bulletin of the W.H.O. 62.1984 p271-291 .
- Giassudin, A.S., M., Boryswick, G., and Absedra, A. (1989) Rotavirus associated diarrhoeal disease in Libyan infants up to one year of age . The 8th Medical Conference of the Kuwait Medical Association 1989.
- Goldwater , P.N., Chrystie I.L., Banatval. J.E. (1979). Rotavirus and the respiratory tract. B.Med. J. 2:1551 .
- Guarino, A., Guandalini, S., Al-bano, F., Mascia, A.,G.,Rubino. A. (1991). Enteral immunoglobulins for treatment of protracted rotaviral diarrhoea pediatric . Infect. Dis J. 10:612 .
- Gurwith , M., Wenman, W.,Hinde , D., Felthman , S., and Greenberg, H. (1981) . A prospective study of rotavirus infection in infants and young children . J. infect. Dis. 144:218 .
- Hart C.A. and Ibrahim O.S. (1989). Rotavirus and gastroenteritis . Postgraduate Doctor 1989 12:252 .
- Hanson , L.A., Hofvander , Y., Lindquist , B., Zetterstrom. R. (1985). Breast feeding as a protection against gastro-enteritis and other infections . Acta.Pediat. Scand.74:641.
- Hassony , H.J., and Abdul-Aziz S.M. (1989). Rotavirus among childhood diarrhoea in Basrah . Med. J. Basrah University .
- Ho, M.S., Glass, R.I. , Pinsky , P.F , Anderson , L.J. (1989). Rotavirus as a cause of diarrhoea morbidity and mortality in the United States . J. Infect. Dis. 158:1112.
- Hyams, J.S., Krause , P.J. , and Gleason , P.A.,(1981). Lactose malabsorption following rotavirus infection in young children . J. Pediatr. 98:316 .
- Kapikian , A.Z., Kim, H.W., Wyatt, R.G., Cline , W.L., Arrobio, J.O., Brandt, C.D. , Rodriguez, W.J., Sack , D.A. , Chanock , R.M. , and Parrott , R.H., and chanok , R.M. (1980). Approaches to immunization of infants and young children against gastroenteritis due to rotavirus , Rev. Infect. Dis. 2:159.
- Keidon I. , Shift I. , Kerem G. Passwell J.H., (1992) Pediat. Infect. Dis. Jour. 11:773 .
- Kim K.H Yang-J-M. Joo-S-I. Cho-Y-G. Glass-RI. Cho-Y-G. Importance of rotavirus and adenovirus type 40 and 41 in acute gastroenteritis in Korean children J. Clini-Microbiol . 1990 . 28:2279 .
- Lewis, H.M. , Parry J.U., Davies , H.A., Parry, R.D. , Mott A. , Dourmashkin , R. R., Sanderson , P.J, Tyrell , D.A.J, and valman. H.B. (1979). A year-experence of the ritavirus syndrome and it's association with respiratory illness . Arch. Dis Child. ; 54:339 .
- Mitchell, J. , and Skelton , M. M. (1988) . Diarrhoeal infections. 37:195.
- Nabeel I. A. , Al-Hadithi . T., Al-Atar. A. 1986 . Rotavirus and acute infectious gastro-enteritis in children uder five years of age: 77 .
- Maki, M. (1981) . A prospective clinical study of rotavirus diarrhoea in young children. Acta. Pediatr. Scand 71:107 .
- Persson , B.L. , Thoren A. , Tufvesson, B. and Walder , M. (1982) . Diarrhoea Swedish infants . Acta. Pediatr . Scand 71:909 .
- Robert M.K., Stanly A.P. Rotavirus . Nelson Text Book of Pediatric . 14th ed. USA: W.P . Saunders Company 1992:831.
- Ruuska, T., and Vesikari , T. (1990). Rotavirus disease in finish children: use of numerical scores for clinical serverity of diarrhoea episodes. Scand. J. Infect. Dis. 22:259.
- Saulsbury , F.T., Winkelstein , J.A., and Yolken , R.H., (1980). Chronic Rotavirus infection in immune deficiency . J. Pediatr. 97:61.
- Sengupta , P.G., Sen, D., Saha, M.R., Niyogi , S., Deb, B.C., Pal, S.C., (1981) . An epidemic of Rotavirus diarrhoea in Manipure India Transactions of the Royal Society of tropical Medicine and hygiene. 75:521.
- Shephered R.W., Traslow, S., Walker-Smith, J.A, Bird, R., cutting, W., Darnell , R., and barker, C. M. (1975). Infantile gastroenteritis : A clinical study of reovirus-like agent infection. Lancet, 2:1082 .
- Stoll, B.J., Glass, R.I., Bane, H., Huq, M., Khan, M.U.,Ahned, H. (1983) . Vlue of stool examination in patients with diarrhoea Br. Med. J. 28:2037.
- Soenarto , Y. , Sebodo, T. Suryantoro , P. , Krisnomurti , Haksohusodo , S. Uyas , Kusniyo , Ristanto , Romas , M. A., Noerhajati , Muswiroh , S., Rohde, J.E., Ryan , N.J., Luke, R.K.J., Barnes, G.L., and Bishop, R.F., (1983). Bacteria , parasitic agents and Rotavirus associated with acute diarrhoea in hospital inpatient Indonesian children. Royal Socity of Tropical Medicine and hygiene . 77:724.
- Tallet , S., Mackenzie, C. , Middleton , P., Kerzner, B., and Hamilton, R., (1977) Clinical, laboratory and epidemiological features of viral gastroenteritis in infants and children . Pediatr. 60:217.
- Thouless, M.E., Bryden, A.S. , Flewett , T.H., (1977) . Rotavirus neutralization by human milk Br. Med. J. 4:1390.
- Uhnoo, I., E., olding stenkvist, and A., Kveugev (1986). Clinical features of acute gastroenteritis associated with rotavirus , enteric adenoviruses , and bacteria Arch. Dis. Child. 61:732 .
- Walker-Smith. J., (1978. Rotavirus gastroenteritis .Arch. Dis child 53:355 .
- Waller , D.K., Samad Talukolar , M.A. , Carvalho, A.N., and Al-Amawy , A.M., O.(1984) . Rotavirus diarrhoea among pediatric inpatients at armed forced hospital , Riyadh . Saudi. Medical Journal 5:49.
- Weinbery, R.J., Tipton , G.Klish, W.J., and Brown , M.R., (1984). Effect of breast feeding on morbidity of Rotavirus gastroenteritis , Pediatric , 74:250.
- Williams, E.K., Lohr., J.A., and Guerrant, R.L.,(1986). Acute infectious diarrhoea , diagnosis treatment and prevention . Pediatr. Infect. Dis. 3:244.
- Yolken, R.H., Wyatt, R.G. , Mata, L. , Urrutia, J.J., Garcia , B., Chabock , , R.M. , and Kapikian , A.Z. (1978). Secretary Antibody directed against rotavirus in human milk measurement by means of enzyme-linked immunosorbent assay J. Pediatr. 93:916.
