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Abstract
Methods : Throughout a period of 5 years – 50 cases which were proved and diagnosed by brain CT scan , brain MRI and histopathological examination as cases of deep-seated malignant brain tumor " malignant glioma , Astrocytoma Grade III , IV " I divided these 50 cases into 2 groups , the 1st group was 25 cases which was treated by burr-hole biopsy plus deep X. therapy while 2nd group was treated by formal , classical craniotomy flap with subtotal excision of the tumor plus deep . X. therapy all the cases were operated Al-Kadhimyah Teaching Hospital , Al-Mosawy private hospital and Al-Saady Hospital in the Al-Basra city .
Result : We found there is no wide difference between these two neurosurgical methods in relation to the median survival in treatment of the deep-seated malignant brain tumor .
Conclusion : The use of surgical technique of a burr hole plus D.X.T indicated the need for the use of the steriostatic surgery , therefore that a burr-hole plus D. X. T is to be recommended as a usual method of neurosurgery to treat a deep-seated malignant brain tumor " Astrocytoma Grade III , IV .
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References
- James C D, Carlbom E , Dumonski jp , et al clonol genomic alterations in glcoma malignancy stages . Concer res 48 : 5546 – 5551 , 1988 .
- James CD , Carlbom , Nordenskjold M , et al : mitotic recombination of chromosome 17 in astrocytomas . Proc. Nat/ Acad Sci USA 86 : 2858 – 2862 , 1989 .
- Davis F, Freels , S , Grutch J . et al survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histologic type : An analysis based on surveillance, Epidemiology , and End results ( SEER) data , 1973 – 1991 J Neurosurg . 88 : 1 – 10 , 1998 .
- Cohen A , Modan B : Some epidemiologic aspects of neoplastic disease in Israeli immigrant population 3. Brain tumors cancer 22 : 1323 – 1328 , 1968 .
- Troillas P , menaud G, De , the G , et al : ( Epidemiological study of primary tumors of the neuraxis in the Rhone-Alps region Qualitative data on the etiology and geographical distribution of 1670 tumors ) Neural ( paris ) 131 : 691 – 707 , 1975 .
- Mao Y , Desmeules M , Semenciw RM , et al . Increasing brain cancer rates in Canada CMAJ 145 : 1583 – 1591 , 1991 .
- Ohasgbulam SC , Saddegi N , Ikerionwus : intracranial tumors in Enugu Nigeria . Cancer 46 : 2322 , 1980 .
- Cheng MK : Brain tumors in the peoples Republic of China : A statistical review . Neurosurgery 10 : 16 – 21 , 1982 .
- Davis DL , Hoel D, Foxj , Lopez A : International trends in cancer mortality in France , west Germany , Italy , Japan , England and Wales , and the USA ( see comments ) Lancet 336 : 474 – 481 , 1990
- Burger PC , Heinz ER , Shibata T . et al Topographic anatomy and CT correlations in the untreated glioblastoma mulforme . J Neurosurg 68 : 698 – 704 , 1988 .
- Scherer HJ : The forms of growth in glwmas and their practical significance Brain 63 : 1 – 35 . 1940 .
- Scherer HJ : cerebral astroytomas and their derivatives . As J cancer 4 : 159 – 198 , 1940 .
- Nazzaro JM , Neuwelt EA : The role of surgery in the management of supratentorial intermediate and high . grade astrocytomas in a dults . J Neurosurg 73 : 331 – 334 , 1940
- Bernstien JJ , Goldberg WJ : Rapid migraton of grafted cortical astrocytoma from suspension gnofts placed in host thoralic spinal cord Brain Res 401 : 205 – 211 , 1989
- Bernstein JJ , Gold berg WJ , Laws ER et al : C6 gliomes cell invasion and migration of rat brain after neural homografting ultrastructur Neurosourg 26 : 622 – 628 , 1990 .
- Bernstein JJ , Laws EN Levine KV , et al C6 glcome astrocytoma cell and fetal astrocyte migration into an artificial basement membrane : A permissive substrate for neural tumors but not fetal astrocytes . Neurosurgeny 28 : 652 – 658 . 1991 .
References
James C D, Carlbom E , Dumonski jp , et al clonol genomic alterations in glcoma malignancy stages . Concer res 48 : 5546 – 5551 , 1988 .
James CD , Carlbom , Nordenskjold M , et al : mitotic recombination of chromosome 17 in astrocytomas . Proc. Nat/ Acad Sci USA 86 : 2858 – 2862 , 1989 .
Davis F, Freels , S , Grutch J . et al survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histologic type : An analysis based on surveillance, Epidemiology , and End results ( SEER) data , 1973 – 1991 J Neurosurg . 88 : 1 – 10 , 1998 .
Cohen A , Modan B : Some epidemiologic aspects of neoplastic disease in Israeli immigrant population 3. Brain tumors cancer 22 : 1323 – 1328 , 1968 .
Troillas P , menaud G, De , the G , et al : ( Epidemiological study of primary tumors of the neuraxis in the Rhone-Alps region Qualitative data on the etiology and geographical distribution of 1670 tumors ) Neural ( paris ) 131 : 691 – 707 , 1975 .
Mao Y , Desmeules M , Semenciw RM , et al . Increasing brain cancer rates in Canada CMAJ 145 : 1583 – 1591 , 1991 .
Ohasgbulam SC , Saddegi N , Ikerionwus : intracranial tumors in Enugu Nigeria . Cancer 46 : 2322 , 1980 .
Cheng MK : Brain tumors in the peoples Republic of China : A statistical review . Neurosurgery 10 : 16 – 21 , 1982 .
Davis DL , Hoel D, Foxj , Lopez A : International trends in cancer mortality in France , west Germany , Italy , Japan , England and Wales , and the USA ( see comments ) Lancet 336 : 474 – 481 , 1990
Burger PC , Heinz ER , Shibata T . et al Topographic anatomy and CT correlations in the untreated glioblastoma mulforme . J Neurosurg 68 : 698 – 704 , 1988 .
Scherer HJ : The forms of growth in glwmas and their practical significance Brain 63 : 1 – 35 . 1940 .
Scherer HJ : cerebral astroytomas and their derivatives . As J cancer 4 : 159 – 198 , 1940 .
Nazzaro JM , Neuwelt EA : The role of surgery in the management of supratentorial intermediate and high . grade astrocytomas in a dults . J Neurosurg 73 : 331 – 334 , 1940
Bernstien JJ , Goldberg WJ : Rapid migraton of grafted cortical astrocytoma from suspension gnofts placed in host thoralic spinal cord Brain Res 401 : 205 – 211 , 1989
Bernstein JJ , Gold berg WJ , Laws ER et al : C6 gliomes cell invasion and migration of rat brain after neural homografting ultrastructur Neurosourg 26 : 622 – 628 , 1990 .
Bernstein JJ , Laws EN Levine KV , et al C6 glcome astrocytoma cell and fetal astrocyte migration into an artificial basement membrane : A permissive substrate for neural tumors but not fetal astrocytes . Neurosurgeny 28 : 652 – 658 . 1991 .