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June 19, 2021
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June 19, 2021
Published
June 19, 2021
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Abstract

The activity of alkaloids compound extracted from Chlorophyta and Cyanophyta were test against pathogenic bacteria and fungi without parasites ,thus, the present study has aimed to test the activity of alkaloids as antiparasite for the first time in Iraq and against Hydatidosis among the world .The present study has resulted that 2-(N,N- dimethylhydrazino)cyclohexanecarbonitrile compound has activity against the protoscolices at five days –post treatment in  vitro and in low concentration from that used with albendazole. 

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References

  1. - Dar, F.K. and Alkarmi ,T. Alkarmi . (1997). Public health aspects of cystic echinococcosis in the Arab countries. Acta. Tropica. 67 : 125-132.
  2. - Akhan , O. ; Ensari , S. and Ozmen, M. (2002) . Precutaneous treatment of a period gland hydatid cyst . Eur. Radiol. , 12: 597-599.
  3. - Georgopoulos , S. ; Korres, S. ; Riga, M. and Ferekidis, E. (2007). Hydatid cyst in the bile duct of the submandibular gland. Int. J. Oral. Surg. , 36: 177 – 179.
  4. - Buttenschoen K, Carli Buttenschoen D. Echinococcus granulosus infection: the challenge of surgical treatment.Langenbecks Arch Surg 2003; 4:218-30.
  5. - Morar , R. and Feldman , C. (2003). Pulmonary echinococcosis . Eur. Respir. J. , 21 : 1069 – 1077.
  6. - McManus , D.P. ; Zhang, W. and Li, J. (2003). Echinococcosis. Parasitology . J. , 18: 1295 – 1304.
  7. - Romig T,(2003) Epidemiology of echinococcosis, Langenbecks Arch Surg.;388:209-17
  8. - PARIJA, S.C. & SHEELA DEVI, C.(1999) - Current concepts in the diagnosis of cystic echinococcosis in humans and Livestocks and intestinal echinococcosis in canine hosts. J. vet. Parasit., 13: 93-102..
  9. - Morar , R. and Feldman , C. (2003). Pulmonary echinococcosis . Eur. Respir. J. , 21 : 1069 – 1077.
  10. Kladi, M.; Vagias, C.; Stavri, M.; Rahman, M.M.; Gibbons, S.; Roussis, V.(2008) C15 acetogenins with antistaphylococcal activity from the red alga Laurencia glandulifera. Phytochem. Lett., 1, 31–36.
  11. Lorena V. Leَn-Deniz1, Eric Dumonteil2, Rosa Moo-Puc1,3, and Yolanda Freile-Pelegrin1.(2009). Antitrypanosomal in vitro activity of tropical marine algae extracts . Pharmaceutical Biology,; 47(9): 864–871.
  12. Schaeffer, D.J.; Krylov, V.S.(2000) Anti-HIV activity of extracts and compounds from algae and cyanobacteria. Ecotoxicol. Environ. Saf., 45, 208–227.
  13. Smit AJ (2004). Medicinal and pharmaceutical uses of seaweed natural products: A review. J. Appl. Phycol. 16: 245-262.
  14. - Goud, J.P.; Se Shikala, D. and Singara Charya, M.A. (2007). Antibacterial activity and bimolecular composition of certain fresh water microalgae from river Godovari (India). Sci. Wor. J., 2 3: 19 – 23.
  15. Tan, B. K. H. and Vanitha, J. (2004). Immunomodulatory and antimicrobial effect of some traditional Chinese medicinal herbs N. Singapore, J. Med., 11: 10 – 15.
  16. Smyth, J. D. (1964). The biology of hydatid organisms. Adv. Parasitol. , 2: 169-219.
  17. - Reichelt, J.L. and M.A. Borowitzka, (1984). Antimicrobial activity from marine algae: Results of a large-scale screening programme. Hydrobiology, 116/117: 158-168.
  18. - Al-Eryani MAY (2002). Comparative study on the efficiency on Ivermectin drug and Peganum harmala seed extract on protoscoleces hydatid cyst. MSc Thesis, Al-Mustansiriya University,Baghdad.
  19. Barzinji AKR, Mothana RA, Nasher AK (2009). Effect of leaf extracts of Dendrosicyos socotrana and Jatropha unicostata on the viability of Echinococcus granulosus protoscoleces. EurAsia J BioSci 3, 16, 122-129.
  20. Shu Y-Z (1998) Recent natural products based drug development:A pharmaceutical industry perspective. J. nat. Prod. 61: 1053–1071.
  21. Nara T, Kamei Y, Tsubouchi A, Annoura T, Hirota K, Lizumi K, Dohmoto Y, Ono T, Aoki T (2004): Inhibitory action of marine algae extracts on the Trypanosoma cruzi dihydroorotate dehydrogenase activity and on the protozoan growth in mammalian cells. Parasitol Int 54: 59–64
  22. Carmichael, W.W., 1992. Cyanobacteria secondary metabolites--the cyanotoxins. J. Appl. Bacteriol.,72(6): 445-459.
  23. Katircioglu, H.; Beyatli, Y.; Aslim, B.; Ksedag, Z. and Atici, T. (2006). Screening for antimicrobial agent production of some microalgae in fresh water. Internet. J. Microbiol. 2.
  24. - Al- Nasir, (2010) .Isolation and Identification of some active compounds from the green alga Cladophora crispata with their bioactivity test .M.Sc.thesis.college of education , university of Basrah.
  25. - Wefky, S. and M. Ghobrial, 2008. Studies on the bioactivity of different solvents extracts of selected marine macroalgae against fish pathogens. Res. J. Microbiol., 3: 673-682.
  26. Blunt JW, Copp BR, Munro MHG, Northcote PT, Prinsep MR (2006): Marine natural products. Nat Prod Rep 23: 26–78.

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