Main Article Content
Abstract
to evaluate the effect of hydrogen peroxide 3% in comparison with iced normal saline on tonsillectomy times, blood loss during the surgery and on the number of packs used.
Methods: Analytical cross sectional study was performed on thirty patients was carried out in the Department of Otolaryngology of AL-Habbobi General Hospital,AL-Nassyria, Iraq, in the period from the 1st week of March 2010 till the last week of November 2010. Tonsillectomy was performed using hydrogen peroxide 3% as a haemostatic agent in Group A(n = 15 tonsils), while in Group B (n = 15 tonsils) iced normal saline was used where as no agent was used with the gauze pack in GroupC(n=30 tonsils).
Results: The application of pack socked with hydrogen peroxide 3% or iced saline in the tonsillar fossae reduced the operation time , the operative blood loss and also reduced the number of packs used in Group A and B in comparison with non agent method . The results were statistically significant.
Conclusion: The local application of 3% hydrogen peroxide on the tonsillar bed after tonsillectomy is beneficial to decreasing the volume of blood loss more than other applications;while no significant difference between group A and B regarding the number of packs used and duration of operation
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References
- Curtin JM. The history of tonsil and adenoid surgery.Otolaryngol Clin North Am 1987; 20:415-419.
- Paradise JL, Bluestone CD, Bachman RZ, Colborn DK,Bernard BS, Taylor FH, et al Efficacy of tonsillectomyfor recurrent throat infection in severely affected children - Results of parallel randomized and nonrandomized clinical trials. N Engl J Med 1984; 310:674-683.
- Curtain MA. The history of tonsils and adenoids.Otolaryngologic Clinic of North America. 1987;20: 60-62.
- Murty GE. Diathermy haemostasis at tonsillectomy:Current practice. J Larygo Otol. 1990; 104:549-52.
- Patai S, Rapporport Z, eds. The syntheses of sulphones, sulphoxides and cyclic sulphides. Chichester, UK: John Wiley and Sons, 1994. p. 112-116.
- Branemark PI, Ekholm R. Tissue injury caused by wound disinfection. J Bone Joint Surg 1967; 49:48-62.
- Lineweaver W, Howard R, Soucy D, McMorris S, Freeman J, Crain C, et al. Topical antimicrobial toxicity.Arch Surg 1985; 120:267-270.
- Guerin S, O’Reilly P, Kelly D. Hydrogen peroxide as an irrigation solution: acomparative study of the effect of hydrogen peroxide versus normal saline on the strength of bone-cement interface in arthroplasty. J Clin Neurosci 2007; 14:488-490.
- Arif Raza Khan, Aziz Khan, Farman Ali1, Shah-e-din1 and Noor Sahib Khan1ENT Department Khyber Teaching Hospital, Peshawar,2ENT Department DHQ Teaching Hospital D.I.Khan, Pakistan Gomal Journal of Medical Sciences Jan–June, 2007, Vol. 5, No. 1
- .Agrawal SR, Jain AK, Marathe D, Agrawal R. The effect of bismuth subgallate a haemostatic agent in tonsillectomy.Indian J Otolaryngol 2005; 57:287-289.
- Chang HJ, Baek SH, Choi CY, Kang SN, Park JB, Lee WY, et al. Hemostatic efficacy of topical application of cold hydrogen peroxide in adenoidectomy. Korean J Otolaryngol - Head Neck Surg 2003; 46:946-949.
- Al-abassi Ahmed M., Zahra K Saeed Hydrogen Peroxide 3%: Is it Beneficial in Tonsillectomy? SULTAN QABOOS UNIVERSITY MEDICAL JOURNAL JULY 2008, VOLUME 8, ISSUE 2, P. 201-204
- Dubey, Prakash K, Singh, Anuj K. Venous oxygen embolism due to hydrogen peroxide irrigation during posterior fossa surgery. J Neurosurg Anesthesiol 2000; 12:54-56
- Kalloo AN, Canto MI, Wadwa KS, Smith CL, Gislason GT, Okolo PI, et al. Clinical usefulness of 3% hydrogenperoxide in acute upper GI bleeding: a pilot study. Gastrointest Endosc 1999; 49:518-21.
References
Curtin JM. The history of tonsil and adenoid surgery.Otolaryngol Clin North Am 1987; 20:415-419.
Paradise JL, Bluestone CD, Bachman RZ, Colborn DK,Bernard BS, Taylor FH, et al Efficacy of tonsillectomyfor recurrent throat infection in severely affected children - Results of parallel randomized and nonrandomized clinical trials. N Engl J Med 1984; 310:674-683.
Curtain MA. The history of tonsils and adenoids.Otolaryngologic Clinic of North America. 1987;20: 60-62.
Murty GE. Diathermy haemostasis at tonsillectomy:Current practice. J Larygo Otol. 1990; 104:549-52.
Patai S, Rapporport Z, eds. The syntheses of sulphones, sulphoxides and cyclic sulphides. Chichester, UK: John Wiley and Sons, 1994. p. 112-116.
Branemark PI, Ekholm R. Tissue injury caused by wound disinfection. J Bone Joint Surg 1967; 49:48-62.
Lineweaver W, Howard R, Soucy D, McMorris S, Freeman J, Crain C, et al. Topical antimicrobial toxicity.Arch Surg 1985; 120:267-270.
Guerin S, O’Reilly P, Kelly D. Hydrogen peroxide as an irrigation solution: acomparative study of the effect of hydrogen peroxide versus normal saline on the strength of bone-cement interface in arthroplasty. J Clin Neurosci 2007; 14:488-490.
Arif Raza Khan, Aziz Khan, Farman Ali1, Shah-e-din1 and Noor Sahib Khan1ENT Department Khyber Teaching Hospital, Peshawar,2ENT Department DHQ Teaching Hospital D.I.Khan, Pakistan Gomal Journal of Medical Sciences Jan–June, 2007, Vol. 5, No. 1
.Agrawal SR, Jain AK, Marathe D, Agrawal R. The effect of bismuth subgallate a haemostatic agent in tonsillectomy.Indian J Otolaryngol 2005; 57:287-289.
Chang HJ, Baek SH, Choi CY, Kang SN, Park JB, Lee WY, et al. Hemostatic efficacy of topical application of cold hydrogen peroxide in adenoidectomy. Korean J Otolaryngol - Head Neck Surg 2003; 46:946-949.
Al-abassi Ahmed M., Zahra K Saeed Hydrogen Peroxide 3%: Is it Beneficial in Tonsillectomy? SULTAN QABOOS UNIVERSITY MEDICAL JOURNAL JULY 2008, VOLUME 8, ISSUE 2, P. 201-204
Dubey, Prakash K, Singh, Anuj K. Venous oxygen embolism due to hydrogen peroxide irrigation during posterior fossa surgery. J Neurosurg Anesthesiol 2000; 12:54-56
Kalloo AN, Canto MI, Wadwa KS, Smith CL, Gislason GT, Okolo PI, et al. Clinical usefulness of 3% hydrogenperoxide in acute upper GI bleeding: a pilot study. Gastrointest Endosc 1999; 49:518-21.